(844) 436-7234info@cibadol.com
Trusted By
Thousands of People
Best CBD Product
Hemp Connoisseur
Available Nationwide
We ship to all 50 states

Cannabinoid Receptors In Canines : Does It Exist?

It may be surprising, but research indicates that every animal possesses an ECS barring insects. This covers mammal species, including you and your canine friend. Canines too have both receptors – CB1 and CB2 spread in the same way all across the body. These cannabinoid receptors work as important receivers which help in the activation of certain biological processes within the body. However, dogs have greater cannabinoid receptors within their brain stem compared to humans. This makes them more susceptible to the strong influence of THC.


Does Your Dog Have An Endocannabinoid System (ECS)?

Dogs possess cannabinoid receptors, therefore it means that they also have an ECS. The endocannabinoid system governs the same physiological mechanisms in dogs as in humans, which include appetite, metabolism, mood, and sleep to name a few. Certain actions of the ECS are more observable in canines than in humans, such as its effect on the hair and the skin. We are more liable to ignore this quality of the ECS as we are a more evolved species and have less hair on the body. But, your dog relies on their ECS to maintain the suppleness and thickness of its fur coat.

This vast signaling network – the ECS made up of endogenous cannabinoids with their receptors and metabolic enzymes that have a huge role in maintaining homeostasis and processing and regulating different bodily functions in cats and dogs. The ECS system resolves the homeostatic balance of the immune and nervous systems together with various organ systems.

Research indicates that a balanced ECS boosts sleep, mood changes, appetite, gait, memory, body temperature, reproduction in both animals and humans, fertility, immunity, and pain perception. Any imbalance in ECS due to endocannabinoid deficiency leads to various negative physical symptoms in dogs including stress, aggression, anxiety, poor appetite, digestive problems (diarrhea, vomiting, or irregular bowels), poor coordination, lethargy, inflammation, and pain. Targeting the endocannabinoids with plant cannabinoids has been found to stimulate similar physiological effects as endocannabinoids, thereby improving systemic wellness.

Also Read: Enjoy The Classic Treat – CBD Infused Orange Creamsicle Smoothie

The Way Cannabinoid Receptors Function In Dogs


Cannabinoid Receptors In Canines
Cannabinoid Receptors In Canines


Cannabinoid receptors in canines cater to the same function as the case of human receptors. When endocannabinoids or phytocannabinoids interact with the CB1 and CB2 receptors, it triggers a chain reaction of a kind. The cannabinoid receptors transmit signals to the cells with which they are attached. These signals active responses within the mind and the body. For instance, when your dog consumes CBD it interacts with its cannabinoid receptors, transmitting a message to its immune cells which are responsible for inflammation and regulating swelling. The response is to decrease swelling surrounding tender regions.

A notable distinction is that in humans there is a huge deposition of cannabinoid receptors within the hippocampus – the brain region that regulates memory and learning, while canines have greater cannabinoid receptors in canines within the brain stem, which is responsible for providing life-sustaining functions such as breathing, sleeping, and heartbeat.

Also Read: CBD For Degenerative Disc Disease

How Does CBD Communicate With The ECS Of Canines

The two primary endocannabinoids within the ECS are Anandamide and 2 Arachidonoylglycerol (2 – AG). These natural endocannabinoids are present in the animal tissue and activate the ECS which results in the positive functioning of the system.  Due to Anandamide and 2-AG, the ECS functions basically.

Sadly, endocannabinoids are at times not able to perform their job effectively. Both 2-AG and Anandamide break down very fast due to an enzyme within the body known as Fatty Acid Amide Hydrolase (FAAH). This causes an imbalance or endocannabinoid deficiency in animals and an underperforming ECS. This makes plant-based cannabinoids effective and beneficial as these phytocannabinoids such as CBD, CBG, CBN and the like can stimulate the cannabinoid receptors the same way as 2-AG and Anandamide do.


What Are The Best CBD Products For Pets?


Cannabinoid Receptors In Canines


At Cibadol, we curate the finest collection of CBD pet products for pet lovers on the market. Our small, medium and large CBD pet tinctures are of varying potencies and strengths of 300 mg, 900mg, and 1800mg based on the health needs of the pets. They are sourced from organically grown hemp and are lab-certified and safe for your animals. These are formulated in a way so that your dog receives the proper dosage whatsoever their size be.

Try dropping them below the tongue for quick results (effects trigger within thirty minutes after dosing). You can also include them in your dog’s meal or make them swallow it following which it will take an hour for its effects to commence.

Also Read: CBD For Plantar Fasciitis: Does It Help

CBD Has A Higher Safety Profile For Animals

CBD (Cannabidiol), the plant compound in abundance in the cannabis plant is well-tolerated by canines irrespective of age, breed, size, or gender. This plant cannabinoid has no psychoactive effects and a less severe effect on the ECS as it does not carry out direct cannabinoid binding the way THC does. Many veterinarians suggest offering CBD to your pets for its multiple wellness support.

CBD can offer these marked benefits due to its interaction with the receptors of the ECS as it connects indirectly with the CB2 receptors and communicates its effects all over the body. What really takes place is that CBD raises the natural endocannabinoid production by changing the working of certain enzymes. CBD enacts by restricting the FAAH enzyme from disintegrating extra anandamide generated within the ECS. This permits the neurotransmitter anandamide to regulate mood and attach to the cannabinoid receptors and deliver effects. This generates positive feelings within our furry friends and facilitates pain alleviation.


Final Thoughts On Cannabinoid Receptors In Canines

It can be debated that without the working of the cannabinoid receptors, the whole endocannabinoid system and the medical benefits of CBD would have been rendered ineffective.

Our pets can function normally and continue with their active lives due to the binding of the endocannabinoids with the cannabinoid receptors – CB1 and CB2. Their significance cannot be underrated as without them it is difficult to envision our survival as well as our furry companions.

Interesting Reads: 

What Is Transcendental Meditation

Face Your Fears With CBD

How To Make CBD Lemon Drink?


*Cannot be used in conjuction with other coupons, promotions or subscriptions.