Cannabidiol (CBD) is a chemical component found in the highest concentration in hemp, which is a close relative of marijuana and comes from the same mother plant (Cannabis Sativa L.). CBD is non-intoxicating; in other words, it does not make people high, but it does allow them to reap the many health benefits that this cannabinoid has to offer. CBD’s one-of-a-kind neurological benefits are the primary reason why this supplement has taken the wellness industry by storm.
CBD interacts with the endocannabinoid system differently than other cannabinoids found in the cannabis plant. Anxiety, inflammation, pain, lethargy, aging, skin and bone injury, brain development, and other health issues are among the conditions that CBD can help with. When taken, it makes a person feel calm without the mind-altering effects that THC has.
CBD vs THC
As previously stated, CBD differs significantly from other cannabinoids or chemicals found in both hemp and marijuana.
While all of the plant’s other active components interact with the nervous system’s two cannabinoid receptors, CB1 and CB2, cannabidiol has relatively little effect on both. CB1 receptors can be found in a variety of brain areas, including those that affect emotion, pain, cognition, and memory. CB2 receptors, on the other hand, help the immune system by regulating inflammatory reactions.
Others promote CBD fallacies on the internet, claiming that it interacts with cannabinoid receptors, although this is absolutely false. CBD encourages the endocannabinoid system to manufacture more cannabinoids while also slowing their breakdown. THC, on the other hand, attaches to CB1 and CB2 receptors, activating them and altering a person’s thinking, memory, pleasure, and pain perception, as well as concentration. These effects lead to the “high” that we call marijuana.
CBD has the potential to affect THC’s effects by inhibiting CB1 receptors in areas where THC binds. THC can cause anxiety and paranoia in some users at greater dosages, which is why many individuals are hesitant to try marijuana. High-CBD strains, on the other hand, tend to reduce these side effects, allowing you to experience the advantages of marijuana without being bothered.
Health Benefits Of CBD
CBD is recognized to have a wide range of medical effects, but because marijuana research is still in its early stages, additional research is needed to fully understand the plant’s constituents. Therefore, we’ve compiled a list of some of the known neurological effects of CBD oil to analyze if it can help you get rid of your symptoms.
CBD’s neuroprotective effects may make it useful in the treatment of neurological illnesses. In other words, CBD protects neurons against degeneration, allowing the brain to age gracefully i.e., enhances brain development. CBD was found to decrease the development of Alzheimer’s symptoms in a study on the disease.
CBD is a pain reliever that is naturally occurring. It has the ability to block neuronal transmission without causing analgesic tolerance or drug addiction. Researchers concluded that CBD and other non-intoxicating cannabinoids can be utilized as a viable alternative to prescription opioid medicines in the treatment of chronic pain as a result of these characteristics.
Furthermore, multiple studies have demonstrated that applying CBD topically to the skin improves joint mobility and speeds up the healing process following an accident. CBD is used by a lot of professional athletes to treat muscle inflammation and other pain-related conditions.
Due to its anticancer effects, very high dosages of CBD can be used to stop cancer cells from growing, which could help treat leukemia and other disorders, according to studies. What’s encouraging about CBD oil’s neurological effects is that it has no toxicity in people.
CBD has long been lauded for its anxiety-relieving properties. In fact, this is the most common reason for people to consume CBD oil. When searching the Internet for positive Cannabidiol voices, you’ll come across a plethora of success stories of people who were able to quit their prescription regimens cold turkey owing to CBD.
In terms of scientific data, 24 patients with social anxiety disorders were assessed in a 2011 study. The patients were given CBD oil or a placebo 1.5 hours before the test. When compared to placebo subjects, anxiety, cognitive impairment, and social discomfort were found to be significantly lower in patients who were given CBD.
CBD And Brain Development
Cannabidiol works through a variety of chemical routes, which explains CBD is beneficial for brain development. Despite the fact that CBD does not bind to two of the cannabinoid receptors, it boosts the endocannabinoid system’s activity in a variety of receptor-independent ways. Certain protein-coupled receptors are also strengthened and inhibited by CBD.
Here’s a basic rundown of how CBD affects different receptor systems.
1. CBD and the Serotonin System
Serotonin receptors have an impact on a variety of physical and mental activities. They influence a person’s cognition, mood, appetite, and pain perception, for example, but they are also responsible for our stress reactions — serotonin receptors control the release of chemicals that control the functions listed above.
CBD works by binding to the serotonin 1A receptor, which is why experts believe it can help with pain, anxiety, and obesity. Furthermore, researchers have connected enhanced activity of serotonin 1A receptors to CBD’s possible impact on depression, chemotherapy-induced nausea, neuropathic pain, and schizophrenia.
2. Vanilloid Receptors and CBD
To produce specific therapeutic effects, CBD binds to vanilloid receptors, also known as TRPV1 receptors. TRPV1 is an ion channel that aids the body in regulating temperature, controlling inflammation, and altering pain perception.
3. CBD and Orphan Receptors
Scientists aren’t clear if the orphan receptor belongs to a larger receptor family, hence its designation. The orphan receptor, also known as GPR55, is in charge of controlling blood pressure, bone density, and bone resorption.
When an orphan receptor is overactive all of the time, it can lead to osteoporosis and contribute to tumor cell proliferation and migration. CBD suppresses GPR55 signalling, which is connected to the cannabinoid’s capacity to decrease cancer growth.
4. CBD and Nuclear Receptors
PPARs, or proliferator-activated receptors, are another name for nuclear receptors. Antitumor properties are thought to be the reason for their activity. CBD activates PPARs, which are receptors present on the nucleus’s surface. When the PPAR-gamma receptor is activated, it causes an antiproliferative response in lung cancer cell families, which has been proven to cause cancer to regress.
5. CBD As An Anandamide Booster
CBD inhibits the breakdown of anandamide in the brain, increasing endocannabinoid levels at synapses, according to a 2016 study published in Frontiers of Pharmacology. Because anandamide and THC have similar molecular structures, anandamide is often referred to as the human counterpart of marijuana. They also produce similar effects; anandamide controls mood, pain perception
THC and anandamide are transported to different areas of the cell via the same intracellular molecules that CBD interacts with. It also has a close relationship with three different types of fatty acid-binding proteins (FABP). The breakdown of anandamide begins as soon as endocannabinoids enter the cell. Cannabidiol inhibits anandamide’s access to the transport protein FABP, delaying its entry into the cell and thereby reducing its breakdown.
Some CBD Products to try
Cibadol is one of the biggest suppliers of CBD products. All their products are tested by third-party labs to give you the best quality CBD. They also make sure all their products contain less than 0.3% THC to avoid any psychoactive effects on the consumer. Their best products include CBD tincture, CBD gummies, CBD muscle gel roll-on, and CBD softgel pills.
Boost Your Gym Performance With CBD