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CBD For Carpal Tunnel Syndrome: What Does The Research Say?

A few people are more susceptible to carpal tunnel syndrome than others on account of the repeated nature of their work. Whether you’re a checker, chef, or copywriter, you’re in the category of elevated risk. Carpal tunnel is an extremely popular ailment that can impact anyone, particularly as many among us are logging greater hours before our computers during working from home. This can raise the chance of carpal tunnel, based on your situation. The carpal tunnel is a slender space in your wrist, extending from elbow to palm of the hand; it contains the median nerve, which gets inflamed with the onset of the syndrome. If you get carpal tunnel, you’re perhaps seeking a way to alleviate your pain and symptoms. There are different options to assist you with your pain; still, numerous people are considering CBD therapy as a beneficial solution.


About Carpal Tunnel Syndrome

Carpal Tunnel Syndrome comprises a condition that happens due to median nerve compression. This is primarily the nerve that runs across your arm’s length, across the carpal tunnel culminating in your hand. Compression of this nerve restricts the quantity of oxygen and blood circulation, causing symptoms like itching, pain, and a burning feeling. Assembly line workers, hairstylists, knitters, and other people working in a profession that needs them to repeat their motion with their hands are frequently at greater risk of contracting the condition. If you have a fractured wrist or any of your family members have small carpal tunnels, you are also at greater risk of acquiring the syndrome.



Carpal Tunnel Syndrome can result from repeated motion, particularly if your hands are under your wrists for the most time. When your wrists lie in this arched position for an extended period, you risk constantly pressing your median nerve. Conditions like diabetes, arthritis, obesity, and hypothyroidism can also lead to Carpal Tunnel Syndrome. Some rare instances can cause pregnant women to get diagnosed with this ailment.



Initially, you might see that your arms get numb at night, and it appears to you that they have gone to sleep. During the morning, you may witness a tingling sensation and numbness in your hand that protrudes to your shoulders. The symptoms may deteriorate during the day as you try to grasp an object with your bent wrist.

Other symptoms comprise greater weakness in your hands, a burning feeling in your thumb and palm, and shock-type feelings that travel to your fingertips. As the condition gets worse, your hand muscles may shrink, weakening your grip power.

CBD For Carpal Tunnel Syndrome
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Muscle cramping and pain can also be prevalent. Bear in mind, the median nerve is extremely vital in hand power and coordination, nerve signals, and sensations in your fingers. These 3 functions will be harmed if this nerve is pressed and is not working correctly.

Shaking your hand during the initial stages might provide some relief. That stated, the technique may begin to become less successful with time.


CBD And Carpal Tunnel Syndrome

There aren’t numerous treatments for Carpal Tunnel Syndrome, though Hemp-related medicines are proving successful in handling the condition. CBD is recognized for its painkilling and anti-inflammatory properties, which makes it useful in treating Carpal Tunnel. The Endocannabinoid System, ECS, is an extensive maze of receptors throughout the body and is known to interact with CBD in medication to deliver a balance in the body. The ECS manages pain perception together with mood regulation, reproduction, and digestion.

CBD communicates with the Endocannabinoid System, indirectly activating the body to manufacture its normal cannabinoids and restricting enzymes that disintegrate it. This way, cannabinoids remain in the circulatory system longer, with CBD being attached to the ECS receptors. CBD for pain management is a considerably better alternative as it does not create intoxicating effects. CBD responds separately with everyone, so it is prudent to do a test trial and begin with a lesser dose as you work your way upwards. Topical CBD products will need to be reused regularly for most relief. Do regard mixing your topical medicine to an oral type of CBD. If you require quick pain relief, then CBD Tinctures and Oils are the way forward.


How Is CBD Beneficial For Carpal Tunnel Syndrome?

Given below are the anecdotal shreds of evidence that prove that CBD is beneficial for carpal tunnel syndrome.


CBD Helps With Nerve Inflammation

Carpal tunnel syndrome is grouped as entrapment neuropathy, causing suppression of the nerve. CTS therapy aims to lower inflammation of the tissues around the nerve in the tunnel.

A study published in the European Journal of Pharmacology has shown considerable immunomodulatory and anti-inflammatory properties of CBD. The propounders of the study gave oral CBD therapy to rats with induced sciatic nerve narrowing and inflammatory pain. Sciatica is another kind of entrapment neuropathy like carpal tunnel syndrome.

The study displayed that CBD lowered hyperalgesia (sensitivity to pain signals) and reduced inflammation within the animal models.

A double-blind clinical trial employing CBD and placebo, and posted in Current Pharmaceutical Biotechnology, discovered that topical CBD application considerably lowered cold, pain, and itchy sensations among subjects. The study examined 29 patients having peripheral neuropathy, a condition with nerve pain that doesn’t arise from the brain.

The research team came to the conclusion that topical CBD use may lower pain and various enfeebling sensations resulting from peripheral neuropathy. They also mentioned that CBD was well-permitted and more efficient than conventional therapies for nerve disease. Nevertheless, peripheral neuropathy is separate from CTS so the outcomes may not be reproduced.

Further clinical examinations on humans are required to decide whether CBD is a successful anti-inflammatory painkiller for CTS.


CBD Is Beneficial For Joint Inflammation

A few studies have informed that carpal tunnel syndrome may happen as a side effect of rheumatoid arthritis.

Arthritis comprises a joint disease activated by chronic inflammation. Continuing arthritis raises the chances of CTS. The inflammation emerging from arthritis may break sensory and motor function tunnels within the wrist. Correctly treated rheumatoid arthritis may aid lower the probability of CTS.

Multiple studies have indicated CBD as the likely therapeutic agent in decreasing systemic inflammation in rat models with affected arthritis.

One such study posted in the European Journal of Pain stated that topical CBD preparations are capable of rheumatoid arthritis. In the study, the rats got a CBD cream, demonstrating a substantial decrease in the redness and swelling of the joints. The research team also observed that CBD lowered pain rating rankings and boosted limb posture over time.

Another cross-study informed that oral CBD uses lessened edema and hyperalgesia in paws of rat models. The propounders surmised that CBD is an attractive option to cannabis application on account of its non-intoxicating effects.

As further clinical human studies are completed on this subject, improved knowledge of how CBD delivers the aforesaid effects may be gained.

Happily, the studies are ongoing. The BMJ Open posted an article that looked for volunteers to examine the efficiency and safety of a CBD/THC solution.

The double-blind trial will evaluate the impact of the cannabinoids on the acuteness of inflammation and chronic pain caused by rheumatoid arthritis for 36 weeks. The study may offer further improvements in CBD’s multiple therapeutic uses if the results turn out positive.


Effects On Endocannabinoid System

The human endocannabinoid system (ECS) comprises G-protein-coupled receptors, cannabinoid receptor 1 (CB1), and cannabinoid receptor 2 (CB2).

Multiple studies have proven the ECS’s modulatory function, which may perform a part in delivering various therapeutic benefits. Moreover, researchers accept that CB1 & CB2 activation employing cannabinoids, like cannabidiol (CBD) and THC, exerts modulatory effects on diseases and conditions.

CB1 & CB2 receptors mainly exist in the peripheral nervous system, central nervous system (CNS), and immune system. The ECS regulates the inflammatory response by restricting immune cell stimulation and immune cell apoptosis (cell death).


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The application of a cannabinoid receptor agonist in a study led to decreased macrophages (white blood cell gathering) during in vivo and in vitro studies. Moreover, the ECS may lower cytokine (signaling proteins) activity. Cannabinoids, like CBD, contain the mechanism to dysregulate cytokine generation of immune cells. This action may aid control inflammation.

The decrease in cytokines and macrophages may affect the inflammatory response, reducing chronic inflammatory pain and other feelings experienced in conditions like neuropathy. Furthermore, an animal study exchanged by the Journal of Experimental Medicine indicated that guiding the peripheral endocannabinoids may have therapeutic value in pain control.

The authors also mentioned that CBD, despite its low binding to the cannabinoid receptors, could regulate glycine receptors which are accountable for the neurotransmission of pain sensations. The study concluded that CBD’s regulation of glycine receptors led to analgesic potency in neuropathic as well as inflammatory pain.


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Wrapping Up

The available body of evidence indicates that CBD may be an effective treatment for Carpal Tunnel Syndrome. CBD is recognized for focussing on symptoms of peripheral neuropathy, like tingling, pain, burning, and itching sensations. Sufferers of carpal tunnel syndrome show similar signs.

Moreover, CBD may be a safe and more successful option than corticosteroids and NSAIDs in the matter of alleviating pain and inflammation in muscles and joints.

If you wish to add CBD to your CTS therapy, discuss with your doctor, or locate an expert who has knowledge of CBD. This will aid you to discover the proper dose for the condition and prevent likely interactions with different medications.

Finally, ensure you purchase CBD from a reliable source such as Cibadol. Research is essential if you want to obtain a top-quality product, particularly in the burgeoning and unregulated market.

Interested Reads:

How Does CBD Affect Heart Arrhythmia?

Does CBD Help With Osteoarthritis?

Does CBD Help Motion Sickness?


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