Cannabidiol (CBD) is a plant-based compound that works as a therapeutic agent. Like tetrahydrocannabinol (THC), it belongs to the same cannabaceae family. But the difference is that CBD does not cause any psychoactivity or dependency. It is effective in treating several health conditions without inducing mind-altering effects. It works for digestive problems, inflammatory disorders, chronic pain, skin conditions, anxiety, insomnia, and epilepsy.
Research also connects CBD oil to rectify fertility issues. Though not enough information supports their link, some studies show that CBD oil can influence your fertility. Through this article, we tend to provide scientific evidence to determine their potential relationship.
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Role Of CBD In Fertility And Reproduction
Every human body has an endocannabinoid system (ECS), a complex cell-signaling system. It involves the activation of receptors by endogenous ligands known as endocannabinoids. These endogenous compounds induce specific physiologic events in different organs and tissues throughout the body.
ECS processing helps regulate critical bodily functions to attain homeostasis. For example, it modulates sleep patterns, stress levels, immunity system, inflammatory response, pain perception, body temperature, and mood swings. The problem arises when the system is deficient and consequently affects internal balance. It is where CBD is beneficial for ECS functioning. CBD binds to receptor sites, promotes endocannabinoid production, and inhibits specific enzymes.
A 2019 study reveals the potential of CBD to modulate ECS activity. According to the research, CBD compensates for ECS deficits and offers tremendous therapeutic effects. While the ECS helps manage chronic pain and neurodevelopment, it could also affect the female reproductive system. It impacts ovarian endocrine secretion, oocyte maturation, and folliculogenesis.
The role of ECS in female reproductive tissues is evident in a 2019 study published in the Journal of Ovarian Research. According to this study, ECS influences oviductal embryo transport, placentation, implantation, and uterine decidualization. There seems to be a complex interplay between the ECS and steroid hormone production and secretion. Exogenous cannabinoids like CBD and THC are also ligands for cannabinoid receptors. Even though they are plant-derived compounds, they can mimic the receptor actions of endocannabinoids like anandamide (AEA) and 2-arachidonoylglycerol (2-AG).
Evidence For Cannabis Use And Fertility
Only a few studies have examined how cannabis components affect male and female fertility. It includes studying certain flavonoids, terpenes, and cannabinoids the plant contains.
In a recent study, THC — the cannabinoid responsible for the high sensational feeling — seemed to reduce ovulation. Researchers found that people using marijuana reduced pregnancy rates compared to participants who did not use cannabis.
According to a different study, smoking cannabis reduced sperm count and concentration by 28%, implying that it can significantly impair male fertility.
While these studies highlight the negative impact of cannabis, there’s no solid evidence that CBD does the same. Since endocannabinoid receptors have been found on female reproductive organs, CBD is more likely to increase fertility. Moreover, some research also suggests that CBD may improve the ability of sperm to fertilize an egg.
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Potential Benefits Of Using CBD For Overall Health
There is growing evidence that CBD could help with several medical conditions, from arthritis to anxiety disorders. It functions as an ECS modulator, aiding the system in addressing flaws. Despite being an exogenous cannabinoid, it has endogenous characteristics. After entering the bloodstream, CBD attaches to cannabinoid receptors, primarily found in the brain and spinal cord. Additionally, it communicates with tissues and organs in the periphery, including the spleen, white blood cells, and the gastrointestinal and urinary systems.
CBD ensures that the body has an adequate supply of endocannabinoids. It heals ECS deficits, mimics endogenous substances, and returns the body to a state of equilibrium. Eventually, CBD is essential in defending us against physical and mental illnesses. The overall CBD health benefits are:
- Ensures sound sleep
- Relieves pain and discomfort
- Enhances concentration
- Improves skin conditions
- Boosts energy levels
- Regulates immune response
- Alleviates anxiety and depression
- Promotes positivity and relaxation
- Controls mood swings
- Maintain homeostasis
Today, CBD is a highly sought-after compound due to its non-intoxicating qualities and therapeutic benefits. Many scientists and researchers believe that CBD can positively influence fertility in the same way it boosts other bodily functions. Since CBD acts as an ECS modulator, it could help regulate your reproductive system.
Endocannabinoids may facilitate the maturation of follicles, improve ovarian function, and enhance sperm’s capacity to fertilize eggs. CBD, which can increase endocannabinoid production, appears to be a beneficial supplement to take while trying to get pregnant. However, more research is necessary to confirm whether CBD can limit or boost fertility.
CBD Oil And Fertility: Safety Concerns
There is no apparent positive or negative effect of CBD on human fertility. But many people believe that CBD can help improve fertility indirectly, and it helps us to become more fertile by enhancing our overall health and wellbeing.
Since research is still in its infancy, there isn’t enough evidence to prove that CBD is safe for a developing fetus. It is best to avoid CBD during the first trimester of pregnancy unless your primary healthcare provider gives you another recommendation. Diarrhea, dizziness, nausea, fatigue, and dry mouth are some side effects associated with long-term use of CBD.
When it comes to marijuana, the American College of Obstetricians and Gynecologists advises against using it while trying to conceive and breastfeeding. Experts state that it may adversely affect embryonic growth during the first trimester of pregnancy. The following are some of the possible effects on your fetus:
- Brain development disruption
- Birth size is smaller
- An increased risk of stillbirth
- Higher chance of being born prematurely
- Childhood behavioral issues
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Conclusion On CBD Oil And Fertility
CBD is a cannabis compound that provides enormous health benefits and could help with the symptoms of any other medical diseases you have. Using CBD is an excellent idea if conception problems have led to the emergence of stress, worry, or any other cognitive problems.
Research shows that women with a history of anxiety disorder are more likely to experience infertility. Depression can also have a detrimental effect by making it harder to become pregnant. However, CBD can help lower the psychological distress induced by your reproductive problem. In the long run, this can assist you in getting pregnant. Before ingesting any new supplement, especially if you’re trying to get pregnant, it is best to speak with a medical practitioner. Depending on your situation, they will be able to advise you on the best course of action.