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CBD vs THC : What Are The Differences?

As the legal use of hemp and other cannabis product grows, customers are getting more inquisitive about the different options. This incorporates cannabidiol (CBD) and tetrahydrocannabinol (THC), two natural compounds found in plants of the Cannabis genus. CBD can be extracted from hemp or cannabis. Hemp and cannabis come from the Cannabis sativa plant. Legal hemp must contain 0.3 percent THC or less. CBD is sold as gels, gummies, oils, supplements, enhancements, and many more. THC is the primary psychoactive compound in cannabis that delivers a high sensation. It can be consumed by smoking cannabis. It’s likewise available in oils, edibles, capsules, tinctures, and many more. Both compounds interact with your body’s endocannabinoid system, however, they have totally different impacts. Let us look at the major differences between CBD vs THC.

CBD vs THC: Major Differences

Check the major differences between CBD and THC:

CBD vs THC: Chemical Structure

Both CBD and THC have precisely the same molecular structure: 21 carbon atoms, 30 hydrogen atoms, and 2 oxygen molecules. A slight difference in how the particles are organized accounts for the different effects on your body. Both CBD and THC are chemically similar to your body’s endocannabinoids. This permits them to interact with your cannabinoid receptors.

The interaction influences the release of neurotransmitters in the brain. Neurotransmitters are chemical compounds responsible for relaying messages between cells and play a major role in pain, immune function, stress, and sleep, to name a few

CBD vs THC: Psychoactive Components

Despite their similar chemical structures, CBD and THC don’t have similar psychoactive effects. CBD is psychoactive but doesn’t produce the high associated with THC. CBD is shown to help with anxiety, depression, and seizures. THC binds with the cannabinoid 1 (CB1) receptors in the brain. It produces a high or sense of euphoria

CBD does not bind strongly to CB1 receptors. It requires THC to bind to the CB1 receptor and, thus, helps in decreasing a portion of the undesirable psychoactive impacts of THC, like euphoria or sedation.

CBD vs THC: Medical Benefits

CBD and THC have large numbers of similar medical benefits. However, CBD doesn’t cause the euphoric effects that occur with THC. A few groups may like to use CBD on account of the absence of this result. In June 2018, the FDA approved Epidiolex, the first prescription medication which consists of CBD. It’s used to treat rare, hard-to-control forms of epilepsy.

CBD is used to treat the different health conditions listed below:

  • Seizures
  • Inflammation
  • Pain
  • Inflammatory Bowel Diseases
  • Nausea
  • Depression
  • Migraine
  • Anxiety
  • Psychosis or Mental Disorders

THC is used to treat various health conditions listed below:

  • Pain
  • Glaucoma
  • Nausea
  • Anxiety
  • Low Appetite
  • Insomnia
  • Muscle Spasticity

CBD vs THC: Legality

While choosing products containing CBD or THC, it is likewise essential to consider their legality. Both CBD and THC are included in the U.S. Controlled Substances Act, which implies that they are not legal under federal law. As of July 2020, 33 states and Washington, D.C. have passed cannabis-related laws making medical cannabis with high levels of THC legal. A few states additionally permit the recreational use of cannabis and THC-containing products.

Despite the fact that CBD in certain forms is legal in many states, the points of the legality of THC or CBD products can vary from one state to another.

CBD vs THC: Side Effects

Different side effects are associated with both CBD and THC. Check the side effects related to both THC and CBD listed below:

THC causes temporary side effects such as:

  • Dry Mouth
  • Red Eyes
  • Anxiety
  • Memory Loss
  • Increased Heart Rate
  • Coordination Problems

The side effects caused by CBD include:

  • Fatigue
  • Weight Loss
  • Dizziness
  • Diarrhea
  • Appetite Change


While CBD can be derived from hemp or cannabis, it is frequently derived from hemp to avoid the addition of a huge amount of THC. THC, on the other hand, is derived from cannabis. CBD derived from marijuana consists of a huge amount of THC, which may not be ideal for individuals who are trying to avoid THC. Some CBD products that are derived from cannabis, for instance, may contain more THC than the label suggests.

Final Thoughts

CBD and THC both have medical benefits. They both are considered safe, yet think about side effects and interactions with different medications you’re taking. Talk to your doctor or certified cannabis or CBD specialist before use and in case if you have any questions.

Interesting Reads:

CBD For Weight Loss: Everything You Need To Know

What is CBDA: CBDA vs CBD

Hemp Protein Benefits: Everything You Need To Know

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